The combined effect of the COVID-19 pandemic on public health, the global economy, and social behavior may augur deeper shifts in our human geography – our distribution around the world. This may seem ironic given today’s widespread border closures and standstill in global transportation, but as the curtain lifts, people will seek to move from poorly governed and ill-prepared ‘red zones’ to ‘green zones’ or places with better medical care. Alternatively, people may relocate to places where involuntary quarantine, whenever it strikes next, is less torturous. In the US, both domestic and international migration were surging before the pandemic, with Gen-Xers and millennials shifting to cheaper, second-tier cities in the Sun Belt or abroad to Latin America and Asia in search of an affordable life. Once quarantines lift and airline prices stand at rock bottom, expect more people across the globe to gather their belongings and buy one-way tickets to counties or countries affordable enough to start fresh.